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Tacrolimus
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Tacrolimus has historically been taken orally to suppress immune system response to and rejection of transplanted organs. In ointment form, it is a nonsteroidal option for inflammatory skin conditions such as eczema.3

In a small clinical study, patients using a topical form of the immunomodulator drug tacrolimus showed some improvement of keloid symptoms, and in a case study a patient using tacrolimus for dermatitis noted resolution of a keloid during treatment.3

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